Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

[Image: see text] Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and cyclic racemic allyl halides. This process affords valuable enantiomerically enriched aryl-substituted cycli...

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Autores principales: González, Jesús, Schäfer, Philipp, Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009026/
https://www.ncbi.nlm.nih.gov/pubmed/32055086
http://dx.doi.org/10.1021/acs.organomet.9b00197
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author González, Jesús
Schäfer, Philipp
Fletcher, Stephen P.
author_facet González, Jesús
Schäfer, Philipp
Fletcher, Stephen P.
author_sort González, Jesús
collection PubMed
description [Image: see text] Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and cyclic racemic allyl halides. This process affords valuable enantiomerically enriched aryl-substituted cyclic allyl products and is compatible with heterocyclic allyl chloride electrophiles.
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spelling pubmed-70090262020-02-11 Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides González, Jesús Schäfer, Philipp Fletcher, Stephen P. Organometallics [Image: see text] Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and cyclic racemic allyl halides. This process affords valuable enantiomerically enriched aryl-substituted cyclic allyl products and is compatible with heterocyclic allyl chloride electrophiles. American Chemical Society 2019-05-10 2019-10-28 /pmc/articles/PMC7009026/ /pubmed/32055086 http://dx.doi.org/10.1021/acs.organomet.9b00197 Text en Copyright © 2019 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle González, Jesús
Schäfer, Philipp
Fletcher, Stephen P.
Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title_full Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title_fullStr Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title_full_unstemmed Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title_short Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
title_sort highly enantioselective hiyama cross-coupling via rh-catalyzed allylic arylation of racemic allyl chlorides
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009026/
https://www.ncbi.nlm.nih.gov/pubmed/32055086
http://dx.doi.org/10.1021/acs.organomet.9b00197
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AT fletcherstephenp highlyenantioselectivehiyamacrosscouplingviarhcatalyzedallylicarylationofracemicallylchlorides

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