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Exploiting next-generation sequencing in antibody selections – a simple PCR method to recover binders

Antibody discovery using invitro display technologies such as phage and/or yeast display has become acornerstone in many research and development projects, including the creation of new drugs for clinical use. Traditionally, after the selection phase, random clones are isolated for binding validatio...

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Detalles Bibliográficos
Autores principales: Ferrara, Fortunato, Teixeira, Andre A., Naranjo, Leslie, Erasmus, M. Frank, D’Angelo, Sara, Bradbury, Andrew R.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009332/
https://www.ncbi.nlm.nih.gov/pubmed/31829073
http://dx.doi.org/10.1080/19420862.2019.1701792