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Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling

Long non-coding RNAs play critical roles in tumour progression. Through analysis of publicly available genomic datasets, we found that MIR22HG, the host gene of microRNAs miR-22-3p and miR-22-5p, is ranked among the most dysregulated long non-coding RNAs in glioblastoma. The main purpose of this wor...

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Detalles Bibliográficos
Autores principales: Han, Mingzhi, Wang, Shuai, Fritah, Sabrina, Wang, Xu, Zhou, Wenjing, Yang, Ning, Ni, Shilei, Huang, Bin, Chen, Anjing, Li, Gang, Miletic, Hrvoje, Thorsen, Frits, Bjerkvig, Rolf, Li, Xingang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009478/
https://www.ncbi.nlm.nih.gov/pubmed/31891366
http://dx.doi.org/10.1093/brain/awz406