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Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our knowledge of which interactions occur in a tumor...

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Detalles Bibliográficos
Autores principales: Kumar, Manu P., Du, Jinyan, Lagoudas, Georgia, Jiao, Yang, Sawyer, Andrew, Drummond, Daryl C., Lauffenburger, Douglas A., Raue, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009724/
https://www.ncbi.nlm.nih.gov/pubmed/30404002
http://dx.doi.org/10.1016/j.celrep.2018.10.047