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Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics
Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our knowledge of which interactions occur in a tumor...
Autores principales: | Kumar, Manu P., Du, Jinyan, Lagoudas, Georgia, Jiao, Yang, Sawyer, Andrew, Drummond, Daryl C., Lauffenburger, Douglas A., Raue, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009724/ https://www.ncbi.nlm.nih.gov/pubmed/30404002 http://dx.doi.org/10.1016/j.celrep.2018.10.047 |
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