Iodine-131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma

Cholangiocarcinoma (CC) is an aggressive liver tumor with limited therapeutic options. Natrium-iodide symporter (NIS) mediates the uptake of iodine by the thyroid, representing a key component in metabolic radiotherapy using iodine-131 ((131)I) for the treatment of thyroid cancer. NIS expression is...

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Detalles Bibliográficos
Autores principales: Brito, Ana Filipa, Abrantes, Ana Margarida, Teixo, Ricardo, Pires, Ana Salomé, Ribeiro, Ana Cláudia, Ferreira, Rafael Fernandes, Mascarenhas, Alexandra, Puga, Tiago, Laranjo, Mafalda, Caramelo, Francisco, Boin, Ilka, Jefferson, Douglas M., Gonçalves, Cristina, Martins, Ricardo, Tavares, Inês, Ribeiro, Ilda Patrícia, Sarmento-Ribeiro, Ana Bela, Ferreira, Isabel Marques, Souza, Doroteia, Tralhão, José Guilherme, Botelho, Maria Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010220/
https://www.ncbi.nlm.nih.gov/pubmed/31922240
http://dx.doi.org/10.3892/ijo.2020.4957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010220/
https://www.ncbi.nlm.nih.gov/pubmed/31922240
http://dx.doi.org/10.3892/ijo.2020.4957

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