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Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering

Neoantigens can be predicted and in some cases identified using the data obtained from the whole exome sequencing and transcriptome sequencing of tumor cells. These sequencing data can be coupled with single-cell RNA sequencing for the direct interrogation of the transcriptome, surfaceome, and pairi...

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Detalles Bibliográficos
Autores principales: Zong, Shan, Mi, Tiejuan, Flores, Leo G., Alpert, Amir, Olivares, Simon, Patel, Krina, Maiti, Sourindra, Mcnamara, George, Cooper, Laurence J. N., Torikai, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010234/
https://www.ncbi.nlm.nih.gov/pubmed/32040512
http://dx.doi.org/10.1371/journal.pone.0228112