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Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering
Neoantigens can be predicted and in some cases identified using the data obtained from the whole exome sequencing and transcriptome sequencing of tumor cells. These sequencing data can be coupled with single-cell RNA sequencing for the direct interrogation of the transcriptome, surfaceome, and pairi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010234/ https://www.ncbi.nlm.nih.gov/pubmed/32040512 http://dx.doi.org/10.1371/journal.pone.0228112 |