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celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish

The use of genetics has been invaluable in defining the complex mechanisms of aging and longevity. Zebrafish, while a prominent model for vertebrate development, have not been used systematically to address questions of how and why we age. In a mutagenesis screen focusing on late developmental pheno...

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Detalles Bibliográficos
Autores principales: Li, Chunmei, Barton, Carrie, Henke, Katrin, Daane, Jake, Treaster, Stephen, Caetano-Lopes, Joana, Tanguay, Robyn L, Harris, Matthew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010407/
https://www.ncbi.nlm.nih.gov/pubmed/31985398
http://dx.doi.org/10.7554/eLife.50523