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celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish
The use of genetics has been invaluable in defining the complex mechanisms of aging and longevity. Zebrafish, while a prominent model for vertebrate development, have not been used systematically to address questions of how and why we age. In a mutagenesis screen focusing on late developmental pheno...
Autores principales: | Li, Chunmei, Barton, Carrie, Henke, Katrin, Daane, Jake, Treaster, Stephen, Caetano-Lopes, Joana, Tanguay, Robyn L, Harris, Matthew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010407/ https://www.ncbi.nlm.nih.gov/pubmed/31985398 http://dx.doi.org/10.7554/eLife.50523 |
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