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The Heat Stability of Hepatitis B Virus: A Chronological Review From Human Volunteers and Chimpanzees to Cell Culture Model Systems

During the World War II jaundice and hepatitis in the US army were observed after vaccination with the yellow fever vaccine containing human plasma for stabilization. This led to first heat experiments with volunteers without knowledge of the causative agents. Finally, experiments of human serum wit...

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Detalles Bibliográficos
Autores principales: Steinmann, Jochen, Steinmann, Joerg, Steinmann, Eike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010596/
https://www.ncbi.nlm.nih.gov/pubmed/32117806
http://dx.doi.org/10.3389/fcimb.2020.00032