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The keratin–desmosome scaffold: pivotal role of desmosomes for keratin network morphogenesis

Desmosome-anchored keratin intermediate filaments (KFs) are essential for epithelial coherence. Yet, desmosomal KF attachment and network organization are still unexplored in vivo. We, therefore, monitored KF network morphogenesis in fluorescent keratin 8 knock-in murine embryos revealing keratin en...

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Detalles Bibliográficos
Autores principales: Moch, Marcin, Schwarz, Nicole, Windoffer, Reinhard, Leube, Rudolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010626/
https://www.ncbi.nlm.nih.gov/pubmed/31243490
http://dx.doi.org/10.1007/s00018-019-03198-y