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Chronic irradiation of human cells reduces histone levels and deregulates gene expression

Over the past decades, there have been huge advances in understanding cellular responses to ionising radiation (IR) and DNA damage. These studies, however, were mostly executed with cell lines and mice using single or multiple acute doses of radiation. Hence, relatively little is known about how con...

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Detalles Bibliográficos
Autores principales: Lowe, Donna J., Herzog, Mareike, Mosler, Thorsten, Cohen, Howard, Felton, Sarah, Beli, Petra, Raj, Ken, Galanty, Yaron, Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010678/
https://www.ncbi.nlm.nih.gov/pubmed/32042076
http://dx.doi.org/10.1038/s41598-020-59163-4