An optimized workflow for single-cell transcriptomics and repertoire profiling of purified lymphocytes from clinical samples

Establishing clinically relevant single-cell (SC) transcriptomic workflows from cryopreserved tissue is essential to move this emerging immune monitoring technology from the bench to the bedside. Improper sample preparation leads to detrimental cascades, resulting in loss of precious time, money and...

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Detalles Bibliográficos
Autores principales: Hanamsagar, Richa, Reizis, Timothy, Chamberlain, Mathew, Marcus, Robert, Nestle, Frank O., de Rinaldis, Emanuele, Savova, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010687/
https://www.ncbi.nlm.nih.gov/pubmed/32042039
http://dx.doi.org/10.1038/s41598-020-58939-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010687/
https://www.ncbi.nlm.nih.gov/pubmed/32042039
http://dx.doi.org/10.1038/s41598-020-58939-y

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