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The endocannabinoid hydrolase FAAH is an allosteric enzyme

Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FAAH monomers likely allows both subunits to simulta...

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Detalles Bibliográficos
Autores principales: Dainese, Enrico, Oddi, Sergio, Simonetti, Monica, Sabatucci, Annalaura, Angelucci, Clotilde B., Ballone, Alice, Dufrusine, Beatrice, Fezza, Filomena, De Fabritiis, Gianni, Maccarrone, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010751/
https://www.ncbi.nlm.nih.gov/pubmed/32041998
http://dx.doi.org/10.1038/s41598-020-59120-1