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STAT3 activates MSK1-mediated histone H3 phosphorylation to promote NFAT signaling in gastric carcinogenesis

Epigenetic abnormalities contribute significantly to the development and progression of gastric cancer. However, the underlying regulatory networks from oncogenic signaling pathway to epigenetic dysregulation remain largely unclear. Here we showed that STAT3 signaling, one of the critical links betw...

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Detalles Bibliográficos
Autores principales: Qi, Hongyan, Yang, Zhiyi, Dai, Chujun, Wang, Runan, Ke, Xinxin, Zhang, Shuilian, Xiang, Xueping, Chen, Kailin, Li, Chen, Luo, Jindan, Shao, Jimin, Shen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010763/
https://www.ncbi.nlm.nih.gov/pubmed/32041943
http://dx.doi.org/10.1038/s41389-020-0195-2