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Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients

Down syndrome (DS) is frequently comorbid with congenital heart disease and has recently been shown to reduce the sedative effect of benzodiazepine (BDZ)-class anesthesia but this effect in a clinical setting has not been studied. Therefore, this study compared midazolam sedation after heart surgery...

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Detalles Bibliográficos
Autores principales: Matsuishi, Yujiro, Sakuramoto, Hideaki, Hoshino, Haruhiko, Shimojo, Nobutake, Enomoto, Yuki, Mathis, Bryan J., Hiramatsu, Yuji, Inoue, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010829/
https://www.ncbi.nlm.nih.gov/pubmed/32041972
http://dx.doi.org/10.1038/s41598-020-58283-1