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Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients
Down syndrome (DS) is frequently comorbid with congenital heart disease and has recently been shown to reduce the sedative effect of benzodiazepine (BDZ)-class anesthesia but this effect in a clinical setting has not been studied. Therefore, this study compared midazolam sedation after heart surgery...
Autores principales: | Matsuishi, Yujiro, Sakuramoto, Hideaki, Hoshino, Haruhiko, Shimojo, Nobutake, Enomoto, Yuki, Mathis, Bryan J., Hiramatsu, Yuji, Inoue, Yoshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010829/ https://www.ncbi.nlm.nih.gov/pubmed/32041972 http://dx.doi.org/10.1038/s41598-020-58283-1 |
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