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TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

Tumor necrosis factor (TNF)-α-stimulated protein 6 (TSG-6) is a secreted protein with diverse tissue protective and anti-inflammatory properties. We aimed to investigate its effects in treating mice with alcoholic hepatitis (AH) and the associated mechanisms. AH was induced in 8–10 week female C57BL...

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Detalles Bibliográficos
Autores principales: Wan, Yue-Meng, Wu, Hua-Mei, Li, Yu-Hua, Xu, Zhi-Yuan, Yang, Jin-Hui, Liu, Chang, He, Yue-Feng, Wang, Men-Jie, Wu, Xi-Nan, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010862/
https://www.ncbi.nlm.nih.gov/pubmed/32116692
http://dx.doi.org/10.3389/fphar.2020.00010