Cellular dosimetry of [(177)Lu]Lu-DOTA-[Tyr(3)]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity

BACKGROUND: Survival and linear-quadratic model fitting parameters implemented in treatment planning for targeted radionuclide therapy depend on accurate cellular dosimetry. Therefore, we have built a refined cellular dosimetry model for [(177)Lu]Lu-DOTA-[Tyr(3)]octreotate ((177)Lu-DOTATATE) in vitr...

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Detalles Bibliográficos
Autores principales: Tamborino, Giulia, De Saint-Hubert, Marijke, Struelens, Lara, Seoane, Dayana C., Ruigrok, Eline A. M., Aerts, An, van Cappellen, Wiggert A., de Jong, Marion, Konijnenberg, Mark W., Nonnekens, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010903/
https://www.ncbi.nlm.nih.gov/pubmed/32040783
http://dx.doi.org/10.1186/s40658-020-0276-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010903/
https://www.ncbi.nlm.nih.gov/pubmed/32040783
http://dx.doi.org/10.1186/s40658-020-0276-5

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