Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment

The voltage-gated Kv7.2/Kv7.3 potassium channel is a critical regulator of neuronal excitability. It is strategically positioned at the axon initial segment (AIS) of neurons, where it effectively inhibits repetitive action potential firing. While the selective accumulation of Kv7.2/Kv7.3 channels at...

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Detalles Bibliográficos
Autores principales: Hefting, Louise Leth, D’Este, Elisa, Arvedsen, Emil, Benned-Jensen, Tau, Rasmussen, Hanne Borger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010958/
https://www.ncbi.nlm.nih.gov/pubmed/32116557
http://dx.doi.org/10.3389/fncel.2020.00010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010958/
https://www.ncbi.nlm.nih.gov/pubmed/32116557
http://dx.doi.org/10.3389/fncel.2020.00010

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