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Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment
The voltage-gated Kv7.2/Kv7.3 potassium channel is a critical regulator of neuronal excitability. It is strategically positioned at the axon initial segment (AIS) of neurons, where it effectively inhibits repetitive action potential firing. While the selective accumulation of Kv7.2/Kv7.3 channels at...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010958/ https://www.ncbi.nlm.nih.gov/pubmed/32116557 http://dx.doi.org/10.3389/fncel.2020.00010 |