The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB

Cell-free DNA (cf.DNA) is a powerful noninvasive biomarker for cancer and prenatal testing, and it circulates in plasma as short fragments. To elucidate the biology of cf.DNA fragmentation, we explored the roles of deoxyribonuclease 1 (DNASE1), deoxyribonuclease 1 like 3 (DNASE1L3), and DNA fragment...

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Detalles Bibliográficos
Autores principales: Han, Diana S.C., Ni, Meng, Chan, Rebecca W.Y., Chan, Vicken W.H., Lui, Kathy O., Chiu, Rossa W.K., Lo, Y.M. Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010979/
https://www.ncbi.nlm.nih.gov/pubmed/32004449
http://dx.doi.org/10.1016/j.ajhg.2020.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010979/
https://www.ncbi.nlm.nih.gov/pubmed/32004449
http://dx.doi.org/10.1016/j.ajhg.2020.01.008

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