The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight

OBJECTIVE: Regulation of food intake and energy balance depends on a group of hypothalamic neurons that release anorexigenic melanocortins encoded by the Pomc gene. Although the physiological importance of central melanocortins is well appreciated, the genetic program that defines the functional ide...

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Detalles Bibliográficos
Autores principales: Hael, Clara E., Rojo, Daniela, Orquera, Daniela P., Low, Malcolm J., Rubinstein, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011018/
https://www.ncbi.nlm.nih.gov/pubmed/32180559
http://dx.doi.org/10.1016/j.molmet.2020.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011018/
https://www.ncbi.nlm.nih.gov/pubmed/32180559
http://dx.doi.org/10.1016/j.molmet.2020.01.007

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