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oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity

Oncolytic viruses are promising immunoreagents. Numerous studies have shown that oncolytic virotherapy is effective for many tumors. Herein, we investigated the therapeutic effect of oHSV2, an oncolytic type 2 herpes simplex virus, on mouse colon carcinoma. The in vivo antitumor efficacy of oHSV2 wa...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Hu, Xiao, Liang, Jing, Zhu, Yujie, Zeng, Beibei, Feng, Lin, Zhao, Changyun, Liu, Shangmei, Liu, Binlei, Zhang, Kaitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011019/
https://www.ncbi.nlm.nih.gov/pubmed/32055679
http://dx.doi.org/10.1016/j.omto.2019.12.012