UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues

Polycyclic aromatic hydrocarbons (PAHs) are potent carcinogens and are a primary risk factor for the development of lung and other aerodigestive tract cancers in smokers. The detoxification of PAHs by glucuronidation is well-characterized for the UDP-glycosyltransferase (UGT) 1A, 2A, and 2B subfamil...

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Detalles Bibliográficos
Autores principales: Vergara, Ana G., Watson, Christy J.W., Chen, Gang, Lazarus, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011115/
https://www.ncbi.nlm.nih.gov/pubmed/31836608
http://dx.doi.org/10.1124/dmd.119.089284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011115/
https://www.ncbi.nlm.nih.gov/pubmed/31836608
http://dx.doi.org/10.1124/dmd.119.089284

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