E2F4 functions as a tumour suppressor in acute myeloid leukaemia via inhibition of the MAPK signalling pathway by binding to EZH2

Acute myeloid leukaemia (AML) is an aggressive and mostly incurable haematological malignancy with frequent relapse after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcome. Here, we aim to study the dysregulation of a parti...

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Detalles Bibliográficos
Autores principales: Feng, Yubin, Li, Lanlan, Du, Yan, Peng, Xiaoqing, Chen, Feihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011140/
https://www.ncbi.nlm.nih.gov/pubmed/31943751
http://dx.doi.org/10.1111/jcmm.14853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011140/
https://www.ncbi.nlm.nih.gov/pubmed/31943751
http://dx.doi.org/10.1111/jcmm.14853

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