Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles

BACKGROUND: TP53 mutations occur in only about 3% of primary and 10–20% of relapse B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). However, alternative mechanisms may contribute to functionally impairing the p53 pathway in the absence of a mutation. Candidate mechanisms include overexpress...

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Detalles Bibliográficos
Autores principales: Oh, Lixian, Hainaut, Pierre, Blanchet, Sandrine, Ariffin, Hany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011217/
https://www.ncbi.nlm.nih.gov/pubmed/32041553
http://dx.doi.org/10.1186/s12885-020-6599-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011217/
https://www.ncbi.nlm.nih.gov/pubmed/32041553
http://dx.doi.org/10.1186/s12885-020-6599-8

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