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Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity

BACKGROUND: Diabetic nephropathy (DN), a complication of diabetes, is the result of high glucose-induced pathological changes in podocytes, such as epithelial-mesenchymal transition (EMT). Autophagy is an important mechanism of podocyte repair. Ginsenoside Rg1, the active ingredient of ginseng extra...

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Detalles Bibliográficos
Autores principales: Shi, Yimin, Gao, Yanbin, Wang, Tao, Wang, Xiaolei, He, Jiaxin, Xu, Jiayi, Wu, Bingjie, Li, Yimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011395/
https://www.ncbi.nlm.nih.gov/pubmed/32082395
http://dx.doi.org/10.1155/2020/1903627