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Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling

BACKGROUND: There are seven insulin-like growth factor binding proteins (IGFBPs) that bind insulin-like growth factors (IGFs). IGFBP like protein1 (IGFBPL1) is a new member of this family. The function and mechanism of IGFBPL1 in esophageal cancer remains to be elucidated. METHODS: Eight esophageal...

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Detalles Bibliográficos
Autores principales: Liu, Yingge, Zhang, Meiying, He, Tao, Yang, Weili, Wang, Lidong, Zhang, Lirong, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011530/
https://www.ncbi.nlm.nih.gov/pubmed/32041673
http://dx.doi.org/10.1186/s13148-020-0815-x