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Reprogrammed astrocytes display higher neurogenic competence, migration ability and cell death resistance than reprogrammed fibroblasts

The direct reprogramming of somatic cells into induced neural progenitor cells (iNPCs) has been envisioned as a promising approach to overcome ethical and clinical issues of pluripotent stem cell transplantation. We previously reported that astrocyte-derived induced pluripotent stem cells (iPSCs) ha...

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Detalles Bibliográficos
Autores principales: Xia, Xiaohuan, Li, Chunhong, Wang, Yi, Deng, Xiaobei, Ma, Yizhao, Ding, Lu, Zheng, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011554/
https://www.ncbi.nlm.nih.gov/pubmed/32071715
http://dx.doi.org/10.1186/s40035-020-0184-6