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Cathelicidin preserves intestinal barrier function in polymicrobial sepsis

OBJECTIVES: The intestinal epithelium compartmentalizes the sterile bloodstream and the commensal bacteria in the gut. Accumulating evidence suggests that this barrier is impaired in sepsis, aggravating systemic inflammation. Previous studies reported that cathelicidin is differentially expressed in...

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Detalles Bibliográficos
Autores principales: Ho, Jeffery, Chan, Hung, Liang, Yonghao, Liu, Xiaodong, Zhang, Lin, Li, Qing, Zhang, Yuchen, Zeng, Judeng, Ugwu, Felix N., Ho, Idy H. T., Hu, Wei, Yau, Johnny C. W., Wong, Sunny H., Wong, Wai Tat, Ling, Lowell, Cho, Chi H., Gallo, Richard L., Gin, Tony, Tse, Gary, Yu, Jun, Chan, Matthew T. V., Leung, Czarina C. H., Wu, William K. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011568/
https://www.ncbi.nlm.nih.gov/pubmed/32041659
http://dx.doi.org/10.1186/s13054-020-2754-5