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Mammalian gene expression variability is explained by underlying cell state

Gene expression variability in mammalian systems plays an important role in physiological and pathophysiological conditions. This variability can come from differential regulation related to cell state (extrinsic) and allele‐specific transcriptional bursting (intrinsic). Yet, the relative contributi...

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Detalles Bibliográficos
Autores principales: Foreman, Robert, Wollman, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011657/
https://www.ncbi.nlm.nih.gov/pubmed/32043799
http://dx.doi.org/10.15252/msb.20199146