Retooling Asymmetric Conjugate Additions for Sterically Demanding Substrates with an Iterative Data-Driven Approach

[Image: see text] The development of catalytic enantioselective methods is routinely carried out using easily accessible and prototypical substrates. This approach to reaction development often yields asymmetric methods that perform poorly using substrates that are sterically or electronically dissi...

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Detalles Bibliográficos
Autores principales: Brethomé, Alexandre V., Paton, Robert S., Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011729/
https://www.ncbi.nlm.nih.gov/pubmed/32064147
http://dx.doi.org/10.1021/acscatal.9b01814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011729/
https://www.ncbi.nlm.nih.gov/pubmed/32064147
http://dx.doi.org/10.1021/acscatal.9b01814

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