Ultrahigh verapamil-loaded controlled release polymeric beads using superamphiphobic substrate: D-optimal statistical design, in vitro and in vivo performance

Controlled-release multiparticulate systems of hydrophilic drugs usually suffer from poor encapsulation and rapid-release rate. In the present study, ultra-high loaded controlled release polymeric beads containing verapamil hydrochloride (VP) as hydrophilic model drug were efficiently prepared using...

Descripción completa

Detalles Bibliográficos
Autores principales: Yousry, Carol, Amin, Maha M., Elshafeey, Ahmed H., El Gazayerly, Omaima N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011826/
https://www.ncbi.nlm.nih.gov/pubmed/29902922
http://dx.doi.org/10.1080/10717544.2018.1482974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011826/
https://www.ncbi.nlm.nih.gov/pubmed/29902922
http://dx.doi.org/10.1080/10717544.2018.1482974

Ejemplares similares