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Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression

Context: Indigofera suffruticosa Miller (Fabaceae) and I. truxillensis Kunth produce compounds, such as isatin (ISA) and indirubin (IRN), which possess antitumour properties. Their effects in mammalian cells are still not very well understood. Objective: We evaluated the activities of ISA and/or IRN...

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Detalles Bibliográficos
Autores principales: Fogaça, Manoela Viar, Cândido-Bacani, Priscila de Matos, Benicio, Lucas Milanez, Zapata, Lara Martinelli, Cardoso, Priscilla de Freitas, de Oliveira, Marcelo Tempesta, Calvo, Tamara Regina, Varanda, Eliana Aparecida, Vilegas, Wagner, de Syllos Cólus, Ilce Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011876/
https://www.ncbi.nlm.nih.gov/pubmed/28738722
http://dx.doi.org/10.1080/13880209.2017.1354387