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Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

In connection with our research program on the development of novel indolin-2-one-based anticancer candidates, herein we report the design and synthesis of different series of hydrazonoindolin-2-ones 3a-e, 5a-e, 7a-c, and 10a-l. The synthesised derivatives were in vitro evaluated for their anti-prol...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., Al-Wabli, Reem I., Almutairi, Maha S., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A., Attia, Mohamed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011955/
https://www.ncbi.nlm.nih.gov/pubmed/29707975
http://dx.doi.org/10.1080/14756366.2018.1462802