Secondary amine selective Petasis (SASP) bioconjugation

Selective modification of proteins enables synthesis of antibody-drug conjugates, cellular drug delivery and construction of new materials. Many groups have developed methods for selective N-terminal modification without affecting the side chain of lysine by judicious pH control. This is due to lowe...

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Detalles Bibliográficos
Autores principales: Sim, Yonnette E., Nwajiobi, Ogonna, Mahesh, Sriram, Cohen, Ryan D., Reibarkh, Mikhail Y., Raj, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012053/
https://www.ncbi.nlm.nih.gov/pubmed/32110356
http://dx.doi.org/10.1039/c9sc04697f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012053/
https://www.ncbi.nlm.nih.gov/pubmed/32110356
http://dx.doi.org/10.1039/c9sc04697f

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