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DNA Hypermethylation Downregulates Telomerase Reverse Transcriptase (TERT) during H. pylori-Induced Chronic Inflammation

Helicobacter pylori infection causes chronic gastritis and is the major risk factor of gastric cancer. H. pylori induces a chronic inflammation-producing reactive oxygen species (ROS) which is a source of chromosome instabilities and contributes to the development of malignancy. H. pylori also promo...

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Detalles Bibliográficos
Autores principales: Bussière, Françoise I., Michel, Valérie, Fernandes, Julien, Costa, Lionel, Camilo, Vania, Nigro, Giulia, De Reuse, Hilde, Fiette, Laurence, Touati, Eliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012206/
https://www.ncbi.nlm.nih.gov/pubmed/32082377
http://dx.doi.org/10.1155/2019/5415761