Anti-PLA2R1 Antibodies Containing Sera Induce In Vitro Cytotoxicity Mediated by Complement Activation

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic membranous nephropathy (MN). However, the pathogenic role of anti-PLA2R1 autoantibodies is unclear. Our aim was to evaluate the in vitro cytotoxicity of anti-PLA2R1 antibodies mediated by complement. Forty-eight patients w...

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Detalles Bibliográficos
Autores principales: Lateb, Maël, Ouahmi, Hajar, Payré, Christine, Brglez, Vesna, Zorzi, Kevin, Dolla, Guillaume, Zaidan, Mohamad, Boyer-Suavet, Sonia, Knebelmann, Bertrand, Crépin, Thomas, Courivaud, Cécile, Jourde-Chiche, Noémie, Esnault, Vincent, Lambeau, Gérard, Seitz-Polski, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012209/
https://www.ncbi.nlm.nih.gov/pubmed/32083137
http://dx.doi.org/10.1155/2019/1324804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012209/
https://www.ncbi.nlm.nih.gov/pubmed/32083137
http://dx.doi.org/10.1155/2019/1324804

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