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Melatonin Reverses the Loss of Stemness Induced by TNF-α in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression

Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and disease treatment. However, long-term in vitro culture results in loss of MSC stemness. The inflammation that occurs at stem cell transplant sites (such as that resulting from TNF-α) is a contributing factor for stem...

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Detalles Bibliográficos
Autores principales: Wang, Xudong, Liang, Tongzhou, Qiu, Jincheng, Qiu, Xianjian, Gao, Bo, Gao, Wenjie, Lian, Chengjie, Chen, Taiqiu, Zhu, Yuanxin, Liang, Anjing, Su, Peiqiang, Peng, Yan, Huang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012241/
https://www.ncbi.nlm.nih.gov/pubmed/32082385
http://dx.doi.org/10.1155/2019/6568394