Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates

Human respiratory syncytial virus (RSV) and parainfluenza virus type 3 (HPIV3) are among the most common viral causes of childhood bronchiolitis and pneumonia worldwide, and lack effective antiviral drugs or vaccines. Recombinant (r) HPIV3 was modified to express the RSV fusion (F) glycoprotein, the...

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Detalles Bibliográficos
Autores principales: Liu, Xueqiao, Liang, Bo, Liu, Xiang, Amaro-Carambot, Emerito, Surman, Sonja, Kwong, Peter D., Graham, Barney S., Collins, Peter L., Munir, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012412/
https://www.ncbi.nlm.nih.gov/pubmed/32045432
http://dx.doi.org/10.1371/journal.pone.0228572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012412/
https://www.ncbi.nlm.nih.gov/pubmed/32045432
http://dx.doi.org/10.1371/journal.pone.0228572

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