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MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

The 2016 World Health Organization classification defines diffuse large B-cell lymphoma (DLBCL) subtypes based on Epstein-Barr virus (EBV) infection and oncogenic rearrangements of MYC/BCL2/BCL6 as drivers of lymphomagenesis. A subset of DLBCL, however, is characterized by activating mutations in MY...

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Detalles Bibliográficos
Autores principales: Vermaat, Joost S., Somers, Sebastiaan F., de Wreede, Liesbeth C., Kraan, Willem, de Groen, Ruben A.L., Schrader, Anne M. R., Kerver, Emile D., Scheepstra, Cornelis G., Berenschot, Henriëtte, Deenik, Wendy, Wegman, Jurgen, Broers, Rianne, de Boer, Jan-Paul D., Nijland, Marcel, van Wezel, Tom, Veelken, Hendrik, Spaargaren, Marcel, Cleven, Arjen H., Kersten, Marie José, Pals, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012469/
https://www.ncbi.nlm.nih.gov/pubmed/31123031
http://dx.doi.org/10.3324/haematol.2018.214122