Molecular quantification of tissue disease burden is a new biomarker and independent predictor of survival in mastocytosis

A high allele burden of the KIT D816V mutation in peripheral blood or bone marrow aspirates indicates multi-lineage hematopoietic involvement and has been associated with an aggressive clinical course of systemic mastocytosis. Since mast cells are substantially underrepresented in these liquid speci...

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Detalles Bibliográficos
Autores principales: Greiner, Georg, Gurbisz, Michael, Ratzinger, Franz, Witzeneder, Nadine, Class, Svenja Verena, Eisenwort, Gregor, Simonitsch-Klupp, Ingrid, Esterbauer, Harald, Mayerhofer, Matthias, Müllauer, Leonhard, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012478/
https://www.ncbi.nlm.nih.gov/pubmed/31018976
http://dx.doi.org/10.3324/haematol.2019.217950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012478/
https://www.ncbi.nlm.nih.gov/pubmed/31018976
http://dx.doi.org/10.3324/haematol.2019.217950

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