Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

Hereditary spherocytosis (HS) originates from defective anchoring of the cytoskeletal network to the transmembrane protein complexes of the red blood cell (RBC). Red cells in HS are characterized by membrane instability and reduced deformability and there is marked heterogeneity in disease severity...

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Detalles Bibliográficos
Autores principales: Huisjes, Rick, Makhro, Asya, Llaudet-Planas, Esther, Hertz, Laura, Petkova-Kirova, Polina, Verhagen, Liesbeth P., Pignatelli, Silvia, Rab, Minke A.E., Schiffelers, Raymond M., Seiler, Elena, van Solinge, Wouter W., Corrons, Joan-LLuis Vives, Kaestner, Lars, Mañú-Pereira, Maria, Bogdanov, Anna, van Wijk, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012482/
https://www.ncbi.nlm.nih.gov/pubmed/31147440
http://dx.doi.org/10.3324/haematol.2018.188151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012482/
https://www.ncbi.nlm.nih.gov/pubmed/31147440
http://dx.doi.org/10.3324/haematol.2018.188151

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