Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch

Post-translational control of PERIOD stability by Casein Kinase 1δ and ε (CK1) plays a key regulatory role in metazoan circadian rhythms. Despite the deep evolutionary conservation of CK1 in eukaryotes, little is known about its regulation and the factors that influence substrate selectivity on func...

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Detalles Bibliográficos
Autores principales: Philpott, Jonathan M, Narasimamurthy, Rajesh, Ricci, Clarisse G, Freeberg, Alfred M, Hunt, Sabrina R, Yee, Lauren E, Pelofsky, Rebecca S, Tripathi, Sarvind, Virshup, David M, Partch, Carrie L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012598/
https://www.ncbi.nlm.nih.gov/pubmed/32043967
http://dx.doi.org/10.7554/eLife.52343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012598/
https://www.ncbi.nlm.nih.gov/pubmed/32043967
http://dx.doi.org/10.7554/eLife.52343

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