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Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart

Heart failure remains a major health burden around the world. Despite great progress in delineation of molecular mechanisms underlying development of disease, standard therapy has not advanced at the same pace. The multifunctional signaling molecule Ca(2+)/calmodulin-dependent protein kinase II (CaM...

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Detalles Bibliográficos
Autores principales: Nassal, Drew, Gratz, Daniel, Hund, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012788/
https://www.ncbi.nlm.nih.gov/pubmed/32116711
http://dx.doi.org/10.3389/fphar.2020.00035