High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration

High pressure below 100 MPa interferes inter-molecular interactions without causing pressure denaturation of proteins. In Escherichia coli, the binding of the chemotaxis signaling protein CheY to the flagellar motor protein FliM induces reversal of the motor rotation. Using molecular dynamics (MD) s...

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Detalles Bibliográficos
Autores principales: Hata, Hiroaki, Nishihara, Yasutaka, Nishiyama, Masayoshi, Sowa, Yoshiyuki, Kawagishi, Ikuro, Kitao, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012829/
https://www.ncbi.nlm.nih.gov/pubmed/32047226
http://dx.doi.org/10.1038/s41598-020-59172-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012829/
https://www.ncbi.nlm.nih.gov/pubmed/32047226
http://dx.doi.org/10.1038/s41598-020-59172-3

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