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High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration
High pressure below 100 MPa interferes inter-molecular interactions without causing pressure denaturation of proteins. In Escherichia coli, the binding of the chemotaxis signaling protein CheY to the flagellar motor protein FliM induces reversal of the motor rotation. Using molecular dynamics (MD) s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012829/ https://www.ncbi.nlm.nih.gov/pubmed/32047226 http://dx.doi.org/10.1038/s41598-020-59172-3 |