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Complementary roles of murine Na(V)1.7, Na(V)1.8 and Na(V)1.9 in acute itch signalling

Acute pruritus occurs in various disorders. Despite severe repercussions on quality of life treatment options remain limited. Voltage-gated sodium channels (Na(V)) are indispensable for transformation and propagation of sensory signals implicating them as drug targets. Here, Na(V)1.7, 1.8 and 1.9 we...

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Detalles Bibliográficos
Autores principales: Kühn, Helen, Kappes, Leonie, Wolf, Katharina, Gebhardt, Lisa, Neurath, Markus F., Reeh, Peter, Fischer, Michael J. M., Kremer, Andreas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012836/
https://www.ncbi.nlm.nih.gov/pubmed/32047194
http://dx.doi.org/10.1038/s41598-020-59092-2